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DC Field | Value | Language |
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dc.contributor.author | Oliveira, Edward José de | pt_BR |
dc.contributor.author | Kanamura, Hermínia Yohko | pt_BR |
dc.contributor.author | Lima, Dirce Mary Correia | pt_BR |
dc.date.accessioned | 2019-09-11T20:58:42Z | - |
dc.date.available | 2019-09-11T20:58:42Z | - |
dc.date.issued | 2005 | - |
dc.citation.volume | 100 | pt_BR |
dc.citation.issue | 4 | pt_BR |
dc.citation.spage | 421 | - |
dc.citation.epage | 425 | - |
dc.identifier.doi | 10.1590/S0074-02762005000400013 | pt_BR |
dc.identifier.issn | 1678-8060 | - |
dc.identifier.uri | http://repositorio.unitau.br/jspui/handle/20.500.11874/1552 | - |
dc.description.abstract | IgM-ELISA is an immunoenzymatic method useful for detection of IgM antibodies against a fraction of Schistosoma mansoni adult worm antigen (AWA) that is soluble in trichloroacetic acid (AWA-TCA). This method was applied to three groups of individuals with different clinical and epidemiological characteristics, and the results compared with those obtained by other diagnostic methods: immunofluorescence test for detection of IgM antibodies (IgM-IFT) or IgG antibodies (IgG-IFT), ELISA for detection of IgG antibodies (IgG-ELISA), and two parasitological methods, Kato-Katz and miracidium hatching. The IgM-ELISA presented a sensitivity of 98%, when the parasitologic fecal examination was defined as reference diagnostic method, and a specificity of 98 and 97.3%, respectively for the group of clinically healthy individuals and other helminth carriers. A comparative analysis between the results of IgM-ELISA and those obtained by other serologic tests showed a good degree of agreement, with Kappa indices ranging from 0.95 to 0.98. The diagnostic efficacy of 97.8%, as determined with schistosomiasis patients with low parasitic burden, suggests the excellent performance of the IgM-ELISA and its usefulness for the diagnosis of schistosomiasis when applied in low endemic areas. | en |
dc.description.provenance | Made available in DSpace on 2019-09-11T20:58:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2005 | en |
dc.language | Inglês | pt_BR |
dc.publisher | Instituto Oswaldo Cruz, Ministério da Saúde | - |
dc.publisher.country | Brasil | pt_BR |
dc.relation.ispartof | Memórias do Instituto Oswaldo Cruz | - |
dc.rights | Acesso Aberto | pt_BR |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | * |
dc.source | Scielo | pt_BR |
dc.subject.other | Schistosoma mansoni | en |
dc.subject.other | immunodiagnosis | en |
dc.subject.other | ELISA | en |
dc.subject.other | IgM antibodies | en |
dc.title | Efficacy of an enzyme-linked immunosorbent assay as a diagnostic tool for schistosomiasis mansoni in individuals with low worm burden | en |
dc.type | Artigo de Periódico | pt_BR |
dc.description.affiliation | [Kanamura, Hermínia Yohko] Universidade de Taubaté, Brasil | - |
dc.description.affiliation | Lima, Dirce Mary Correia] Universidade de São Paulo, Brazil | - |
dc.description.affiliation | Oliveira, Edward José de] Universidade de São Paulo, Brazil | - |
dc.subject.researcharea | Parasitology | en |
dc.subject.researcharea | Tropical Medicine | en |
dc.subject.scieloarea | Parasitology | en |
dc.subject.scieloarea | Tropical Medicine | en |
dc.identifier.scielo | SCIELO:S0074-02762005000400013 | - |
Appears in Collections: | Artigos de Periódicos |
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S0074-02762005000400013.pdf | 448.98 kB | Adobe PDF | View/Open |
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