Please use this identifier to cite or link to this item: http://repositorio.unitau.br/jspui/handle/20.500.11874/3219
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dc.contributor.authorUnterkircher, CSpt_BR
dc.contributor.authorLeao, MVPpt_BR
dc.contributor.authorBlotta, MHSLpt_BR
dc.contributor.authorde Camargo, ZPpt_BR
dc.date.accessioned2019-09-12T16:57:18Z-
dc.date.available2019-09-12T16:57:18Z-
dc.date.issued2004-
dc.citation.volume35pt_BR
dc.citation.issue(1-2)pt_BR
dc.citation.spage59-
dc.citation.epage63-
dc.identifier.issn1517-8382-
dc.identifier.issn1678-4405-
dc.identifier.urihttp://repositorio.unitau.br/jspui/handle/20.500.11874/3219-
dc.description.abstractRecent attention has been focused oil the natural antibodies as a component of natural immunity and as integral part of the idiotypic network. However, their functional role in different infections has rarely been studied. This work was undertaken to investigate the presence of natural antibodies in paracoccidioidomycosis (PCM). In addition, we analyzed anti-P. brasiliensis antibodies and their distribution in IgG subclasses in order to acquire better knowledge about the humoral immune response in this mycosis. Our findings show that the natural antibody response is not very much increased in PCM when compared with other parasite infections and this response is restricted to a few specificities, suggesting that P. brasiliensis moderately triggers CD5+ B cells. The anti-actin antibody was the main antibody specificity found in PCM. Specific antibodies to P. brasiliensis were mainly found in the IgG1 subclass in chronic patients of PCM.en
dc.description.provenanceMade available in DSpace on 2019-09-12T16:57:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2004en
dc.languageInglêspt_BR
dc.publisherSoc Brasileira Microbiologia-
dc.publisher.countryBrasilpt_BR
dc.relation.ispartofBrazilian Journal of Microbiology-
dc.rightsEm verificaçãopt_BR
dc.sourceWeb of Sciencept_BR
dc.subject.otherNatural Antibodiesen
dc.subject.otherParacoccidioides Brasiliensisen
dc.subject.otherParacoccidioidomycosisen
dc.subject.otherImmune-Responseen
dc.subject.otherB-1 Cellsen
dc.subject.otherAutoantibodiesen
dc.subject.otherBrasiliensisen
dc.subject.otherMiceen
dc.subject.otherCd5+en
dc.subject.otherResistanceen
dc.subject.otherInfectionen
dc.subject.otherDiseaseen
dc.titleNatural antibodies in paracoccidioidomycosisen
dc.typeArtigo de Periódicopt_BR
dc.contributor.orcidLeao, Mariella https://orcid.org/0000-0003-1949-3207pt_BR
dc.contributor.orcidCamargo, Zoilo https://orcid.org/0000-0002-2971-7983pt_BR
dc.contributor.researcheridLeao, Mariella/F-7787-2012pt_BR
dc.contributor.researcheridCamargo, Zoilo/C-5305-2013pt_BR
dc.identifier.wosWOS:000234802500009-
dc.description.affiliationUniv Estadual Paulista, Fac Odontol, Dept Biociencias & Diagnost Bucal, Sao Jose Dos Campos, Brazil; Universidade de Taubaté (Unitau), Dept Med; Univ Estadual Campinas, Fac Ciencias Med, Dept Patol Clin, Campinas, SP, Brazil; Escola Paulista Med, Disciplina Biol Celular, BR-04023 Sao Paulo, Brazil-
dc.subject.wosareaMicrobiologyen
dc.subject.researchareaMicrobiologyen
Appears in Collections:Artigos de Periódicos

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