Please use this identifier to cite or link to this item:
metadata.dc.type: Artigo de Periódico
Title: Effects of chlorhexidine preprocedural rinse on bacteremia in periodontal patients: a randomized clinical trial
Authors: Balejo, Rodrigo Dalla Pria
Cortelli, José Roberto
Costa, Fernando Oliveira
Cyrino, Renata Magalhães
Aquino, Davi Romeiro
Cogo-Müller, Karina
Miranda, Taís Browne
Moura, Sara Porto
Cortelli, Sheila Cavalca
Abstract: Abstract Objective: Single dose of systemic antibiotics and short-term use of mouthwashes reduce bacteremia. However, the effects of a single dose of preprocedural rinse are still controversial. This study evaluated, in periodontally diseased patients, the effects of a pre-procedural mouth rinse on induced bacteremia. Material and Methods: Systemically healthy individuals with gingivitis (n=27) or periodontitis (n = 27) were randomly allocated through a sealed envelope system to: 0.12% chlorhexidine pre-procedural rinse (13 gingivitis and 13 periodontitis patients) or no rinse before dental scaling (14 gingivitis and 15 periodontitis patients). Periodontal probing depth, clinical attachment level, plaque, and gingival indices were measured and subgingival samples were collected. Blood samples were collected before dental scaling, 2 and 6 minutes after scaling. Total bacterial load and levels of P. gingivalis were determined in oral and blood samples by real-time polymerase chain reaction, while aerobic and anaerobic counts were determined by culture in blood samples. The primary outcome was the antimicrobial effect of the pre-procedural rinse. Data was compared by Mann-Whitney and Signal tests (p<0.05). Results: In all sampling times, polymerase chain reaction revealed higher blood bacterial levels than culture (p<0.0001), while gingivitis patients presented lower bacterial levels in blood than periodontitis patients (p<0.0001). Individuals who experienced bacteremia showed worse mean clinical attachment level (3.4 mm vs. 1.1 mm) and more subgingival bacteria (p<0.005). The pre-procedural rinse did not reduce induced bacteremia. Conclusions: Bacteremia was influenced by periodontal parameters. In periodontally diseased patients, pre-procedural rinsing showed a discrete effect on bacteremia control.
metadata.dc.language: Inglês
Publisher: Faculdade De Odontologia De Bauru - USP
metadata.dc.rights: Acesso Aberto
metadata.dc.identifier.doi: 10.1590/1678-7757-2017-0112
Issue Date: 2017
Appears in Collections:Artigos de Periódicos

Files in This Item:
File SizeFormat 
S1678-77572017000600586.pdf167.76 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons