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http://repositorio.unitau.br/jspui/handle/20.500.11874/1553
metadata.dc.type: | Artigo de Periódico |
Title: | Application of synthetic peptides in development of a serologic method for laboratory diagnosis of schistosomiasis mansoni |
Authors: | Oliveira, Edward José de Kanamura, Hermínia Yohko Takei, Kioko Hirata, Rosario Dominguez Crespo Nguyen, Nga Yen Hirata, Mário Hiroyuki |
Abstract: | The immunoreactivity of seven peptides synthesized from Schistosoma mansoni proteins, was evaluated by dot-blot and ELISA assays using two different sensitization methodologies. The best results were obtained on wells of the Costar 3590 microplates coated with peptides P1, P2, P3, P6, and P7 using conventional methodology. The signals increased considerably (p < 0.0003) on wells sensitized with P1 to P6 using alternative methodology. In contrast, the well coated with peptide P7 presented lower signal when compared with conventional methodology (p = 0.0019). These results, establish the basis for the application of synthetic peptides for laboratory diagnosis of schistosomiasis mansoni. |
metadata.dc.language: | Inglês |
metadata.dc.publisher.country: | Brasil |
Publisher: | Instituto Oswaldo Cruz, Ministério da Saúde |
metadata.dc.rights: | Acesso Aberto |
metadata.dc.rights.uri: | https://creativecommons.org/licenses/by-nc-nd/4.0 |
metadata.dc.identifier.doi: | 10.1590/S0074-02762006000900058 |
URI: | http://repositorio.unitau.br/jspui/handle/20.500.11874/1553 |
Issue Date: | 2006 |
Appears in Collections: | Artigos de Periódicos |
Files in This Item:
File | Size | Format | |
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S0074-02762006000900058.pdf | 506.55 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License