Please use this identifier to cite or link to this item:
http://repositorio.unitau.br/jspui/handle/20.500.11874/1781
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Brito, Luciana Malheiro de | pt_BR |
dc.contributor.author | Carreira, Cláudia de Moura | pt_BR |
dc.contributor.author | Raldi, Denise Pontes | pt_BR |
dc.contributor.author | Lage-Marques, José Luiz | pt_BR |
dc.contributor.author | Habitante, Sandra Márcia | pt_BR |
dc.contributor.author | Saad, Wilson Abraão | pt_BR |
dc.date.accessioned | 2019-09-12T16:25:57Z | - |
dc.date.available | 2019-09-12T16:25:57Z | - |
dc.date.issued | 2011 | - |
dc.citation.volume | 19 | pt_BR |
dc.citation.issue | 2 | pt_BR |
dc.citation.spage | 113 | - |
dc.citation.epage | 117 | - |
dc.identifier.doi | 10.1590/S1678-77572011000200006 | pt_BR |
dc.identifier.issn | 1678-7765 | - |
dc.identifier.uri | http://repositorio.unitau.br/jspui/handle/20.500.11874/1781 | - |
dc.description.abstract | Nitric oxide (NO) has been considered a key molecule in infammation. OBJECTIVE: The aim of this study was to evaluate the effect of treatment with L-NAME and sodium nitroprussiate, substances that inhibit and release NO, respectively, on tissue tolerance to endodontic irrigants. MATERIAL AND METHODS: The vital dye exudation method was used in a rat subcutaneous tissue model. Injections of 2% Evans blue were administered intravenously into the dorsal penial vein of 14 male rats (200-300 g). The NO inhibitor and donor substances were injected into the subcutaneous tissue in the dorsal region, forming two groups of animals: G1 was inoculated with L-NAME and G2 with sodium nitroprussiate. Both groups received injections of the test endodontic irrigants: acetic acid, 15% citric acid, 17% EDTA-T and saline (control). After 30 min, analysis of the extravasated dye was performed by light absorption spectrophotometry (620 nm). RESULTS: There was statistically signifcant difference (p<0.05) between groups 1 and 2 for all irrigants. L-NAME produced a less intense infammatory reaction and nitroprussiate intensifed this process. CONCLUSIONS: Independently of the administration of NO inhibitors and donors, EDTA-T produced the highest irritating potential in vital tissue among the tested irrigating solutions. | en |
dc.description.provenance | Made available in DSpace on 2019-09-12T16:25:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2011 | en |
dc.language | Inglês | pt_BR |
dc.publisher | Faculdade De Odontologia De Bauru - USP | - |
dc.publisher.country | Brasil | pt_BR |
dc.relation.ispartof | Journal of Applied Oral Science | - |
dc.rights | Acesso Aberto | pt_BR |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | * |
dc.source | Scielo | pt_BR |
dc.subject.other | Nitric oxide | en |
dc.subject.other | Infammation | en |
dc.subject.other | Root canal irrigants | en |
dc.title | Effect of nitric oxide inhibitor and donor substances on the infammatory process caused by endodontic irrigants | en |
dc.type | Artigo de Periódico | pt_BR |
dc.contributor.orcid | LAGE-MARQUES, Jose Luiz https://orcid.org/0000-0003-4356-5610 | pt_BR |
dc.contributor.researcherid | LAGE-MARQUES, Jose Luiz/C-3167-2013 | pt_BR |
dc.description.affiliation | [Carreira, Cláudia de Moura] Universidade de São Paulo, Brazil | - |
dc.description.affiliation | Lage-Marques, José Luiz] Universidade de São Paulo, Brazil | - |
dc.description.affiliation | Brito, Luciana Malheiro de; Raldi, Denise Pontes; Lage-Marques, José Luiz; Habitante, Sandra Márcia; Saad, Wilson Abraão] Universidade de Taubaté, Brazil | - |
dc.subject.researcharea | Dentistry, Oral Surgery & Medicine | en |
dc.subject.scieloarea | Dentistry, Oral Surgery & Medicine | en |
dc.identifier.scielo | SCIELO:S1678-77572011000200006 | - |
Appears in Collections: | Artigos de Periódicos |
Files in This Item:
File | Size | Format | |
---|---|---|---|
SCIELO S1678-77572011000200006.pdf | 63.97 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License